The Mental Health Risks of Adolescent Cannabis Use

Dependence is an underappreciated risk of cannabis use [1]. There has been an increase in the numbers of adults requesting help to stop using cannabis in many developed countries, including Australia [4] and the Netherlands [1, 5]. Regular cannabis users develop tolerance to many of the effects of delta-9-tetrahydrocannabinol [6–8], and those seeking help to stop often report withdrawal symptoms [9–11]. Withdrawal symptoms have been reported by 80% of male and 60% of female adolescents seeking treatment for cannabis dependence

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http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0030039